[Comparison among 5 different extracting methods of Whitmania pigra whitman]

Whitmania pigra whitman is one of the traditional Chinese drugs commonly used in clinical practice for Blood circulation promoting and Stasis relieving, its active principle was unknown yet. In this report, five extracting methods have been studied based on its extract's anticoagulant and antithrombotic activity in vitro. The results have revealed that the extracts using different extracting methods showed different anticoagulant and anti-thrombotic activity. Among them, the extracts produced by water-boiling and alcohol-prepitating have shown the strongest anticoagulant activity and good antithrombotic effect.