[Effects of shenyan yiqiye on experimental membranous glomerulonephritis in rabbits]

The cationic bovine serum albumin (C-BSA) was used for duplicating experimental animal model of membranous glomerulonephritis with chronic renal failure. Shenyan Yiqiye (SYYQY) was adopted for treatment. The results showed that, in the therapeutic group, the urine protein and serum creatinine were reduced as compared with those in pathological group, P < 0.01. The parameter of morphometric analysis of glomeruli such as mean diameter, mean perimeter, mean surface area, mean volume, mean cross sectional area were all decreased, P < 0.01, the number of glomerular proliferative cells and thickness of glomerular capillary wall were all attenuated, P < 0.01, as compared with those in the pathological group. It suggested that SYYQY might alleviate the glomeruli lesions and benefit the renal functions.