[Study on puji ointment in treating 628 cases with second and third-degree burns and its decrustative effect]

Area of Science:

• Dermatology
• Wound Healing
• Pharmacology

Background:

• Second and third-degree burns present significant treatment challenges.
• Conventional burn treatments aim to manage exudate, swelling, and promote healing.
• The efficacy of traditional remedies like Puji ointment (PJO) requires scientific validation.

Purpose of the Study:

• To evaluate the therapeutic efficacy of Puji ointment (PJO) in treating second and third-degree burns.
• To compare PJO's effectiveness against conventional treatments.
• To investigate PJO's specific actions on burn exudate, swelling, and healing.

Main Methods:

• Clinical observation of patients with small-range second and third-degree burns treated with PJO.
• Experimental study on rabbits with third-degree burns, comparing PJO with vaseline gauze (control).
• Assessment of burn healing parameters including exudate, antihydropism, decrustation, pH, and infection prevention.

Main Results:

• PJO application demonstrated significant advantages (P < 0.01) over conventional medicine in reducing exudate, antihydropism, and promoting decrustation.
• In rabbit models, PJO-treated burns showed faster pH normalization and accelerated healing compared to controls (P < 0.01).
• PJO was highly effective in reducing burn exudate and swelling, preventing infection, and speeding up the healing process.

Conclusions:

• Puji ointment (PJO) is a highly effective treatment for small second and third-degree burns.
• PJO offers superior outcomes in managing burn exudate, swelling, and promoting healing.
• The study confirms PJO's specific decrustative function and overall therapeutic benefits for severe burns.