[The bronchodilator action of berodual spray compared to fenoterol and ipratropium bromide sprays]

Berodual (Duovent) was tested in 40 bronchial asthma patients in comparison with a similar group treated with fenoterol. The results of FEV1.0 investigation showed no significant differences: increases of 15% were noted in both groups. In two other groups (40 bronchial asthma cases each) treated with berodual and Atrovent, respectively FEV1.0 values were significantly different: increased by 5% in the Atrovent group, and by 15% in the berodual one. Berodual showed the advantage of inducing the same strong bronchodilation of similar duration, though applied in doses by far smaller than fenoterol or Atrovent. A diminution of the clinical evolution score from 3 to 0.7, an increase by 15%; in FEV1.0, and no changes as regards the immunological tests (IgA, IgG, IgM, Clq, C3) were obtained in the group treated with berodual for 4 weeks.