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The antigen presenting capacity of human epidermal Langerhans cells
J Péguet-Navarro1, C Moulon, D Schmitt
1INSERM U 346, Clinique Dermatologique, Hôpital Edouard-Herriot, Lyon, France.
Cellular and Molecular Biology (Noisy-Le-Grand, France)
|January 1, 1994
Abstract:
Dendritic cells (DC) represent a distinct system of antigen-presenting cells (APC) that function to initiate primary T cell responses and are found as a trace population in both lymphoid and non-lymphoid organs. This paper is focused on some properties of epidermal Langerhans cells (LC), the best characterized non-lymphoid DC. The phenotypic markers of LC are reviewed and their immunological function is presented in view of some recent findings partly obtained in our laboratory.