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Plasmenylethanolamine in human intestinal mucosa detected by an improved method for analysis of phospholipid
K Nakanishi1, E Yasugi, H Morita
1Division of Biochemistry and Nutrition, International Medical Center of Japan, Tokyo.
Abstract:
Analysis of phospholipid and their fatty acid composition of human intestinal mucosa was performed by an method elaborated to analyze the limited amount of sample with 2-dimensional TLC followed by lipid-phosphorus determination. Using this method, plasmenylethanolamine was detected in human intestinal mucosa and accounted for about 7% of phospholipid in small and large intestinal mucosa. The amounts of polyunsaturated fatty acids of phosphatidylethanolamine were higher than those of other phosphoglycerides in intestinal mucosa, hence, inflammation-related eicosanoids may originate from ethanolamine containing phospholipid.