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The bm12 Inducible Model of Systemic Lupus Erythematosus (SLE) in C57BL/6 Mice
Published on: November 1, 2015
Acute sideroblastic anemia in active systemic lupus erythematosus
F J Jiménez-Balderas1, M R Morales-Polanco, L Gutierrez
1Department of Rheumatology, Hospital de Especialidades, Centro Médico Nacional Siglo XXI, México DF, México.
Systemic lupus erythematosus (SLE) can transiently cause sideroblastic anemia (SA). This association, though rare, suggests a shared underlying mechanism, with one patient showing SA resolution after SLE treatment.
Area of Science:
- Hematology
- Rheumatology
- Internal Medicine
Background:
- Systemic lupus erythematosus (SLE) is a chronic autoimmune disease.
- Sideroblastic anemia (SA) is a group of blood disorders characterized by ineffective iron uptake by bone marrow erythroid precursors.
- The co-occurrence of SLE and SA is infrequently reported.
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