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[Non-stimulated cycles and GIFT]

P Barjot1, J Osborn, C King

  • 1Infertility Medical Centre Monash University, Melbourne.

Contraception, Fertilite, Sexualite (1992)
|January 1, 1993
PubMed
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Gamete Intrafallopian Transfer (GIFT) without ovarian stimulation achieved a 15.4% pregnancy success rate in a natural cycle survey. This simplified GIFT protocol offers a viable alternative to ovarian stimulation for infertility treatment.

Area of Science:

  • Reproductive Medicine
  • Infertility Treatments
  • Assisted Reproductive Technologies

Background:

  • Ovarian stimulation is commonly used in assisted reproductive technologies.
  • Natural cycle protocols aim to reduce treatment burden and costs.
  • Gamete Intrafallopian Transfer (GIFT) is an established assisted reproductive technique.

Purpose of the Study:

  • To evaluate the efficacy of a simplified Gamete Intrafallopian Transfer (GIFT) protocol.
  • To assess the success rate of GIFT in natural cycles without ovarian stimulation.
  • To determine if simplified GIFT is a viable alternative to stimulated cycles.

Main Methods:

  • A simplified protocol for GIFT was employed.
  • The study involved a survey of 19 natural cycles.

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  • Oocyte retrieval was performed, followed by GIFT procedure.
  • Main Results:

    • 13 oocyte recoveries were performed.
    • Two pregnancies were achieved following GIFT.
    • The success rate per attempt was 15.4%.

    Conclusions:

    • The simplified GIFT technique in natural cycles demonstrated success.
    • The 15.4% success rate is considered favorable given the patient's clinical context.
    • GIFT without ovarian stimulation presents a potential alternative to stimulated cycles for infertility treatment.