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[Which sedation for minor trauma surgery in children?]
1Service accueil-urgences, CHG, Strasbourg, France.
Insights
Midazolam effectively reduces anxiety and pain in children under 6 during laceration repair. Oral or intranasal administration is recommended for outpatients, offering a safe and effective conscious sedation option.
Area of Science:
- Pediatric Emergency Medicine
- Pharmacology
- Pain Management
Context:
- Laceration repair in children under 6 often causes significant anxiety and pain.
- Local anesthetics manage pain but not anxiety, necessitating conscious sedation.
- Existing sedation methods (nitrous oxide, IM cocktail, IV fentanyl) have drawbacks.
Purpose:
- To evaluate Midazolam as a safe and effective agent for conscious sedation in pediatric laceration repair.
- To compare oral and intranasal Midazolam administration routes for efficacy in reducing anxiety and pain.
Summary:
- Midazolam, a water-soluble benzodiazepine, provides anxiolytic, hypnotic, and anterograde amnestic effects.
- Oral and intranasal Midazolam demonstrated safety and effectiveness in alleviating anxiety in young outpatients.
- Rectal Midazolam showed less efficacy, requiring further investigation before routine use.
Impact:
- Provides a safe and effective alternative for managing pediatric procedural anxiety.
- Highlights optimal administration routes (oral, intranasal) for Midazolam in emergency settings.
- Informs clinical practice for pain and anxiety management in pediatric laceration repair.
Abstract:
Children under 6 often show marked anxiety and physical pain during laceration repair. If locally infiltrated anesthetics usually give a good control of physical pain, they have no effect on anxiety and restlessness for which several medications are available for conscious sedation. Continuous nitrous oxide, intramuscular sedative "cocktail" with meperidine-promethazine-chlorpromazine or intravenous fentanyl have various inconveniences and therefore are not ideal for this purpose. By contrast, Midazolam, a short acting watersoluble benzodiazepine with anxiolitic, hypnotic and anterograde amnestic effect, appears to be a safe and effective treatment when given orally or intranasally for alleviating anxiety in under 6 year-old out-patient in emergency department; its rectal administration appears less effective and needs further studies before to be routinely used.
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