[Myelopeptide-1 stimulates humoral immune response in irradiated mice]

Influence of a new bone marrow substance Myelopeptide-1 on the antibody production in the spleen of irradiated mice (2Gy) was studied. Myelopeptide-1 was inoculated in immunized mice at various periods after irradiation by different schemes. It was shown that the stimulating effect of Myelopeptide-1 depended on peptide dose, inoculation scheme, and period between irradiation and immunization.