[Nuclear morphometric analysis of colorectal adenocarcinoma and its clinicopathologic significance]

A nuclear morphometric analysis was performed on the histologic sections of 64 colorectal adenocarcinomas with a 5-year follow-up. The parameters selected in this study were nuclear area (NA), nuclear perimeter (NP), standard deviation of nuclear area (SDNA), nuclear volume (NV), nuclear diameter of an equivalent circle (ND). No clear correlation was found between the five parameters and the clinicopathologic data of colorectal adenocarcinomas. The five parameters were important prognostic factors in colorectal adenocarcinomas. It was found that the grade II colorectal adenocarcinomas were a heterogenous group and could be divided prognostically into various subgroups by nuclear morphometry.