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Related Experiment Videos

Left ventricular torsional dynamics immediately after mitral valve replacement

A DeAnda1, M R Moon, K L Yun

  • 1Department of Cardiovascular and Thoracic Surgery, Stanford University School of Medicine, CA 94305-5247.

Circulation
|November 1, 1994
PubMed
Summary

Cardiac surgery significantly alters left ventricular (LV) torsion and recoil. These changes, measured by myocardial markers, may help assess intraoperative management techniques and myocardial protection strategies.

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Area of Science:

  • Cardiovascular Surgery
  • Cardiac Physiology
  • Biomedical Engineering

Background:

  • Cardiac operations and cardiopulmonary bypass induce systemic unphysiological effects.
  • Left ventricular (LV) torsional deformation detects subclinical LV dysfunction during acute rejection in humans.
  • Investigated LV systolic torsion and diastolic recoil in a canine model.

Purpose of the Study:

  • To assess changes in LV systolic torsion and diastolic recoil after cardiac surgery.
  • To evaluate the utility of these measurements in assessing intraoperative management.

Main Methods:

  • Placed LV subepicardial myocardial markers in seven dogs.
  • Induced mitral regurgitation and performed videofluoroscopic analysis.
  • Performed chordal-sparing mitral valve replacement and restudied LV function.

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Main Results:

  • Regional maximal systolic torsional deformation significantly decreased post-surgery.
  • Minimal regional systolic torsion increased in specific LV regions.
  • Heterogeneous decreases in torsional deformation observed during early diastolic filling.

Conclusions:

  • Regional systolic torsional deformation and diastolic recoil are significantly perturbed after cardiac operations.
  • These measurements can serve as sensitive tools to evaluate intraoperative management and myocardial protection.