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Cardiac function and dysfunction in hypertension

F M Fouad1

  • 1Department of Cardiovascular Biology, Cleveland Clinic Foundation, OH 44195.

Cleveland Clinic Journal of Medicine
|September 1, 1994
PubMed
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Hypertension impacts cardiac function, affecting cardiac output and left ventricular filling. Monitoring both systolic and diastolic function is crucial for managing hypertension and guiding therapy.

Area of Science:

  • Cardiovascular Medicine
  • Nephrology
  • Internal Medicine

Background:

  • Hypertension is a prevalent condition increasing left ventricular afterload.
  • It significantly impacts cardiovascular system function.

Purpose of the Study:

  • To review the effects of elevated blood pressure on cardiac function.
  • To understand the cardiac implications of hypertension.

Main Methods:

  • Literature review on hypertension and cardiac function.
  • Analysis of studies assessing cardiac output, ventricular function, and compliance.

Main Results:

  • Early hypertension may increase cardiac output with normal volume.
  • Established hypertension often shows normal resting systolic function but reduced filling rates in some patients.

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  • Left ventricular hypertrophy in hypertension is linked to high morbidity, reduced compliance, and altered adrenergic response.

    • Conclusions:

    • Assessing both systolic and diastolic cardiac function is vital for hypertensive patients.
    • Monitoring cardiac function aids in therapy selection and patient management.