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Related Experiment Videos

Hodgkin's disease presenting with digital ischaemia

S M Halpern1, P Todd, J D Kirby

  • 1Department of Dermatology, St Bartholomew's Hospital, London, UK.

Clinical and Experimental Dermatology
|July 1, 1994
PubMed
Summary

Raynaud's phenomenon can be linked to Hodgkin's disease. Treating the lymphoma with chemotherapy and improving acute ischemia with sympathectomy led to symptom remission.

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Area of Science:

  • Vascular Medicine
  • Oncology
  • Rheumatology

Background:

  • Raynaud's disease is a primary condition characterized by exaggerated vasoconstriction.
  • Digital ischemia and gangrene are severe complications of advanced Raynaud's phenomenon.

Observation:

  • A 52-year-old male patient presented with severe Raynaud's phenomenon, including digital ischemia and gangrene.
  • The patient was diagnosed with Hodgkin's disease concurrently with the worsening of his Raynaud's symptoms.

Findings:

  • Cervical sympathectomy provided initial relief from acute ischemic symptoms.
  • Subsequent chemotherapy resulted in significant improvement in Raynaud's phenomenon severity and induced lymphoma remission.

Implications:

  • This case highlights a potential association between Raynaud's phenomenon and Hodgkin's disease.
  • Integrated treatment addressing both vascular and oncological aspects can lead to improved patient outcomes.

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