Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Arterial wall changes in type 2 diabetic subjects

G Geroulakos¹, G Ramaswami, M G Veller

¹Irvine Laboratory, Academic Surgical Unit, St Mary's Medical School, London, UK.

Diabetic Medicine : a Journal of the British Diabetic Association

|August 1, 1994

Summary

Type 2 diabetes is linked to thicker carotid arteries, a potential indicator of cardiovascular risk. This study found increased intima-media thickness in diabetic individuals compared to controls.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Inner-mitochondrial membrane protein PfMPV17 is linked to P. falciparum in vitro resistance to the indoloquinolizidine alkaloid alstonine.

The Journal of antimicrobial chemotherapy·2025

Same author

Antiplasmodial activity of the natural product compounds alstonine and himbeline.

International journal for parasitology. Drugs and drug resistance·2021

Same author

Multifocal arterial disease: clinical implications and management.

Current opinion in cardiology·2020

Same author

Safety of urgent endarterectomy in acute non-disabling stroke patients with symptomatic carotid artery stenosis: an international multicenter study.

European journal of neurology·2018

Same author

Transoral laser surgery for laryngeal carcinoma: has Steiner achieved a genuine paradigm shift in oncological surgery?

Annals of the Royal College of Surgeons of England·2017

Same author

Commentary on "Primary Stenting of the Superficial Femoral Artery in Intermittent Claudication Improves Health Related Quality of Life, Ankle Brachial Index and Walking Distance: 12 Month Results of a Controlled Randomised Multicentre Trial".

European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery·2017

Area of Science:

Vascular Biology
Diabetology
Medical Imaging

Background:

Type 2 diabetes is a growing global health concern.
Cardiovascular disease is a major complication of diabetes.
Intima-media thickness (IMT) is a marker for atherosclerosis and cardiovascular events.

Purpose of the Study:

To investigate arterial ultrasonic appearances in Type 2 diabetes patients.
To measure intima-media thickness (IMT) of common carotid arteries.
To assess the presence of plaque in common and femoral bifurcations.

Main Methods:

High-resolution ultrasound was used to examine 97 subjects with Type 2 diabetes and matched controls.
Common carotid artery intima-media thickness (IMT) was measured 2 cm proximal to the bifurcation.

Related Experiment Videos

Plaque presence was recorded at common and femoral bifurcations.

Main Results:

Mean IMT was significantly higher in Type 2 diabetes subjects (0.82 ± 0.22 mm) compared to controls (0.66 ± 0.13 mm) (p < 0.001).
No correlation was found between IMT and various clinical factors (age, BMI, blood pressure, lipids, HbA1c) in diabetic subjects.
Plaque presence data was recorded but not detailed in the abstract.

Conclusions:

Type 2 diabetes is associated with increased common carotid artery intima-media thickness (IMT).
Elevated IMT in Type 2 diabetes may signify an increased risk of cardiovascular events.
Further research could explore the clinical implications of these findings.