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Fine-needle aspiration of anaplastic thyroid carcinoma with varied cytologic and histologic patterns: a case report
P K Brooke1, M Hameed, M F Zakowski
1Department of Pathology, Memorial Sloan-Kettering Cancer Center, New York, NY 10021.
Diagnostic Cytopathology
|January 1, 1994
Abstract:
Anaplastic carcinoma of the thyroid (ACT) is a rare subtype of thyroid neoplasm. This tumor represents approximately 5-10% of all thyroid malignancies and its poor prognosis has not changed in 25 years. ACT often arises in a long-standing thyroid nodule and has been documented to be associated with a variety of more well-differentiated thyroid carcinomas. We describe the cytologic features of a case in which the patient had a 10-yr history of a thyroid nodule. The ACT in this case had a cytologic and histologic appearance of several different subtypes of thyroid carcinomas.