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Related Experiment Videos

[Malignant atrophic papulosis]

C Voigt1, J Aumiller, W Saeger

  • 1Abteilung Innere Medizin I, Marienkrankenhaus, Hamburg.

Deutsche Medizinische Wochenschrift (1946)
|October 21, 1994
PubMed
Summary
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Malignant atrophic papulosis (Köhlmeier-Dégos

Area of Science:

  • Dermatology
  • Gastroenterology
  • Vascular Medicine

Background:

  • Malignant atrophic papulosis (Köhlmeier-Dégos' disease) is a rare systemic vasculopathy.
  • It is characterized by distinctive skin lesions and gastrointestinal manifestations.

Observation:

  • A 53-year-old woman presented with papules on her trunk and limbs, healing with central scars.
  • She later developed jejunal perforation, revealing white plaque-like lesions on the intestinal serosa.

Findings:

  • Histological examination of skin and jejunal biopsy confirmed malignant atrophic papulosis.
  • The patient experienced ileus due to jejunal perforation.

Implications:

  • Early diagnosis and intervention are crucial for managing this rare condition.

Related Experiment Videos

  • Ticlopidine, a platelet-aggregation inhibitor, showed promise in preventing extracutaneous symptoms.
  • This case highlights the importance of considering systemic vasculopathy in patients with unexplained skin and gastrointestinal issues.