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A proposed structure for 'family 18' chitinases. A possible function for narbonin
1Biocomputing Research Unit, University of Edinburgh, UK.
FEBS Letters
|October 31, 1994
Abstract:
The sequence of narbonin, a leguminous seed protein with the TIM barrel structure but of unknown function, is significantly similar to endo-beta-N-acetylglucosaminidase H from Streptomyces plicatus. This protein is a member of a family of chitinases, 'Family 18' of the glycosyl hydrolases. It is proposed that the catalytic domain of this family has the TIM barrel structure. It is proposed that narbonin has chitinase activity, or has been derived from a chitinase by loss of function.