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Long term administration of testosterone on ascorbic acid metabolism in castrated rats
K T Kumari1, V P Menon, S Leelamma
1Department of Biochemistry, University of Kerala Kariavattom, Trivandrum, India.
Indian Journal of Experimental Biology
|July 1, 1994
Abstract:
Orchidectomy caused a significant decrease in the concentration of ascorbic acid and ascorbic acid-2-sulphate in tissues while administration of testosterone to these animals reverses this effect. Concentration of ascorbic acid in liver in experimental groups correlates with the activity of L-qualano-lactone oxidase and dehydroascorbatase in this tissue.