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Immunotherapeutic modification by an ayurvedic formulation Septilin

C S Rao¹, C Raju, S Gopumadhavan

¹R & D Centre, Himalaya Drug Co, Makali, Bangalore, India.

Indian Journal of Experimental Biology

|August 1, 1994

Summary

Septilin, an Ayurvedic remedy, boosts the immune system by enhancing phagocytic function and humoral response. It offers protection against bacterial infections like E. coli and Staphylococcus aureus sepsis.

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Area of Science:

Immunology
Pharmacology
Ayurvedic Medicine

Background:

Chronic infections pose significant health challenges.
Ayurvedic formulations are increasingly explored for therapeutic potential.
Septilin is an established Ayurvedic formulation for chronic infections.

Purpose of the Study:

To investigate the immunomodulatory effects of Septilin.
To evaluate Septilin's impact on the phagocytic system and humoral immunity.
To assess Septilin's efficacy in combating bacterial infections.

Main Methods:

Animal models (rats and mice) were used to study immune responses.
Septilin's effect on bacterial sepsis (E. coli, Staphylococcus aureus) was assessed.
Phagocytic activity and antibody production were measured.

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Main Results:

Septilin provided significant protection against E. coli and Staphylococcus aureus sepsis.
The formulation enhanced neutrophil phagocytic activity.
Septilin stimulated the reticuloendothelial system and increased antibody titers.
It demonstrated protection against chemically induced immune suppression.

Conclusions:

Septilin exhibits potent immunomodulatory properties.
The Ayurvedic formulation effectively enhances both innate and adaptive immunity.
Septilin shows therapeutic promise for managing chronic infections and boosting immune defenses.