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Related Experiment Videos

Aspirin does not affect exercise performance

G S Roi1, U Garagiola, P Verza

  • 1Dipartimento di Scienze e Tecnologie Biomediche, Università degli Studi di Milano, Ospedale San Raffaele, Segrate.

International Journal of Sports Medicine
|July 1, 1994
PubMed
Summary

A single 1000mg dose of aspirin, plain or buffered, did not significantly impact cardiorespiratory performance or exercise capacity in young men. This study found no performance benefits or detriments from aspirin during submaximal and maximal exercise tests.

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Area of Science:

  • Exercise Physiology
  • Pharmacology

Background:

  • Acetylsalicylic acid (ASA), commonly known as aspirin, is widely used for its analgesic and anti-inflammatory properties.
  • Its potential effects on athletic performance and cardiorespiratory function during exercise remain an area of interest.

Purpose of the Study:

  • To investigate the impact of a single 1000mg dose of acetylsalicylic acid (ASA) on cardiorespiratory performance in young men during graded exercise.
  • To compare the effects of plain aspirin versus chewable buffered aspirin against a placebo.

Main Methods:

  • A single-blind, cross-over study involving 18 young men (9 athletes, 9 untrained).
  • Subjects underwent a progressive maximal exercise test on a cycle ergometer after receiving plain aspirin, buffered aspirin, or placebo.
  • Continuous monitoring of ventilation, oxygen consumption, carbon dioxide output, respiratory rate, and heart rate was performed.

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  • Blood lactate levels were measured to determine the anaerobic threshold.

    • Main Results:

    • No statistically significant differences were observed in any of the measured cardiorespiratory variables or exercise performance metrics between the aspirin treatments and the placebo.
    • The pharmacokinetics of aspirin during exercise were also assessed in a subset of participants, with no performance-related findings reported.

    Conclusions:

    • A single 1000mg dose of either plain or buffered aspirin does not appear to affect cardiorespiratory performance or exercise capacity during submaximal and maximal exercise in young men.
    • These findings suggest that aspirin does not offer a performance-enhancing effect in this context.