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Practical guides. I: Central intravenous additive services

M C Allwood1

  • 1Pharmacy Academic Practice Unit, University of Derby, Mickleover, U.K.

Journal of Clinical Pharmacy and Therapeutics
|June 1, 1994
PubMed
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Centralized intravenous additive services (CIVAs) are vital in UK hospitals. This review details their evolution, benefits, operational aspects, and future trends in pharmacy-controlled parenteral drug services.

Area of Science:

  • Pharmacy Practice
  • Hospital Pharmacy Services
  • Intravenous Therapy

Background:

  • Centralized intravenous additive services (CIVAs) have evolved from specialized aseptic preparations like total parenteral nutrition and cytotoxic drug handling.
  • They are increasingly expanding to encompass a comprehensive range of parenteral drug services within hospital pharmacy settings.

Purpose of the Study:

  • To review the development, benefits, and operational considerations of CIVAs in the UK.
  • To compare national guidelines from the UK and USA influencing CIVA services.
  • To discuss injectable stability and shelf-life assignment for pharmacy-prepared additives.

Main Methods:

  • Literature review of centralized intravenous additive services.
  • Analysis of the evolution from aseptic services to full parenteral drug provision.

Related Experiment Videos

  • Comparison of UK and USA national guidelines for CIVA operation.
  • Discussion on stability and shelf-life determination for intravenous additives.

    • Main Results:

    • CIVAs offer significant benefits through pharmacy-operated, ready-to-administer injectable preparations.
    • Operational aspects including staffing, facilities, methods, technical support, and documentation are crucial for effective CIVA services.
    • National guidelines significantly shape the operational models of CIVA services.

    Conclusions:

    • Pharmacy-controlled intravenous additive services are essential and evolving components of modern hospital pharmacy.
    • Understanding injectable stability is key to assigning appropriate shelf lives for pharmacy-prepared intravenous additives.
    • Future trends will continue to shape the provision of intravenous services under pharmacy control.