Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Autonomic responsivity in generalized social phobia

M B Stein1, G J Asmundson, M Chartier

  • 1Department of Psychiatry, University of Manitoba, Winnipeg, Canada.

Journal of Affective Disorders
|July 1, 1994
PubMed
Summary

Generalized social phobia patients show abnormal autonomic nervous system (ANS) functioning, specifically in blood pressure and heart rate responses during certain tests. Further research is needed to understand autonomic dysfunction in social anxiety disorder.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Long-Range Transverse-Momentum Correlations and Radial Flow in Pb-Pb Collisions at the LHC.

Physical review letters·2026
Same author

Search for Quasiparticle Scattering in the Quark-Gluon Plasma with Jet Splittings in pp and Pb-Pb Collisions at sqrt[s_{NN}]=5.02  TeV.

Physical review letters·2025
Same author

First Measurement of A=4 Hypernuclei and Antihypernuclei at the LHC.

Physical review letters·2025
Same author

Probing Strangeness Hadronization with Event-by-Event Production of Multistrange Hadrons.

Physical review letters·2025
Same author

Measurements of Chemical Potentials in Pb-Pb Collisions at sqrt[s_{NN}]=5.02  TeV.

Physical review letters·2024
Same author

Observation of Medium-Induced Yield Enhancement and Acoplanarity Broadening of Low-p_{T} Jets from Measurements in pp and Central Pb-Pb Collisions at sqrt[s_{NN}]=5.02  TeV.

Physical review letters·2024

Area of Science:

  • Psychiatry
  • Neuroscience
  • Cardiology

Background:

  • Social phobia, or social anxiety disorder, is a common psychiatric condition.
  • Autonomic nervous system (ANS) dysfunction may play a role in the pathophysiology of social phobia.
  • Previous research on ANS functioning in social phobia has yielded mixed results.

Purpose of the Study:

  • To investigate autonomic nervous system (ANS) functioning in patients with generalized social phobia.
  • To compare ANS responses between individuals with generalized social phobia and healthy controls.

Main Methods:

  • Fifteen non-depressed, medication-free subjects with DSM-IV generalized social phobia and 15 healthy controls underwent a series of autonomic function tests.
  • Cardiovascular responsivity to tasks including Valsalva maneuver and isometric exercise was assessed.

Related Experiment Videos

  • Plasma levels of norepinephrine and epinephrine were measured.

    • Main Results:

    • Generalized social phobics demonstrated increased blood pressure responsivity during the Valsalva maneuver.
    • Exaggerated vagal withdrawal was observed in social phobics responding to isometric exercise.
    • Cardiovascular responses to other tested tasks and plasma catecholamine levels were comparable between groups.

    Conclusions:

    • Patients with generalized social phobia exhibit specific abnormalities in autonomic nervous system (ANS) functioning.
    • These findings suggest a potential role for autonomic dysfunction in the pathophysiology of social anxiety disorder.
    • Larger studies utilizing neuropharmacologic probes are recommended for further investigation.