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New aporphine alkaloids from guatteria foliosa
V Mahiou1, F Roblot, R Hocquemiller
1Laboratoire de Pharmacognosie, URA 1843 CNRS (BIOCIS), Faculté de Pharmacie, Université de Paris XI, Châtenay-Malabry, France.
Journal of Natural Products
|July 1, 1994
Abstract:
Four new alkaloids were obtained from Guatteria foliosa, namely, the noraporphines (-)-3-methoxyputerine [1] and (+)-norguattevaline [2], the more highly oxidized (+)-3-methoxyguattescidine [3], and the oxoaporphine 3-methoxyoxoputerine [4]. Among several other known alkaloids also found in this same plant, (-)-3-hydroxynornuciferine, (-)-isoguattouregidine, and argentinine exhibited significant activity against Trypanosoma cruzi.