Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Neonatal rhabdomyosarcoma: the IRS experience

T E Lobe1, E S Wiener, D M Hays

  • 1Integroup Rhabdomyosarcoma Study Committee of the Children's Cancer Group, Memphis, TN.

Journal of Pediatric Surgery
|August 1, 1994
PubMed
Summary

Neonatal rhabdomyosarcoma is rare, but caudal tumors show a favorable prognosis. Other factors like histology or size do not predict outcomes in these infants.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Retraction notice to "Induction of ovulation in idiopathic premature ovarian failure: a randomized double-blind trial" RBMO 15/2 (2007) 215-219.

Reproductive biomedicine online·2023
Same author

Relationship between histopathological lesions and oxidative stress in mice infected with <i>Angiostrongylus costaricensis</i>.

Journal of helminthology·2023
Same author

Retraction Note: Does immediate postpartum curettage of the endometrium accelerate recovery from preeclampsia-eclampsia? A randomized controlled trial.

Archives of gynecology and obstetrics·2022
Same author

Effect of two lytic bacteriophages against multidrug-resistant and biofilm-forming <i>Salmonella</i> Gallinarum from poultry.

British poultry science·2020
Same author

Lavender-thymol as a new topical aromatherapy preparation for episiotomy: A randomised clinical trial.

Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology·2014
Same author

Re-laparotomy after caesarean deliveries: risk factors and how to avoid?

Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology·2014

Area of Science:

  • Pediatric Oncology
  • Cancer Research
  • Neonatal Medicine

Background:

  • Neonatal rhabdomyosarcoma is a rare condition with poorly defined characteristics and optimal treatment strategies.
  • Limited data exists on the specific features and prognostic indicators for this rare pediatric cancer.

Purpose of the Study:

  • To describe the epidemiological and clinical characteristics of neonatal rhabdomyosarcoma.
  • To identify potential prognostic factors and optimal therapeutic approaches for affected neonates.

Main Methods:

  • Analysis of data from 3,217 patients in the Intergroup Rhabdomyosarcoma Study (IRS).
  • Focus on a subgroup of 14 patients diagnosed at less than 30 days of age.
  • Evaluation of patient demographics, tumor histology, size, location, and treatment modalities.

Related Experiment Videos

Main Results:

  • Male gender, Caucasian race, caudal tumors, and embryonal/botryoid or undifferentiated histology were predominant in neonates.
  • Approximately 50% of neonates survived, with no significant predictive value found for histology, tumor size, or surgery type.
  • Tumor necrosis and small round cell configuration were associated with a poor prognosis irrespective of histology.
  • Neonatal rhabdomyosarcoma originating in the caudal region demonstrated a favorable prognosis.

Conclusions:

  • Neonatal rhabdomyosarcoma exhibits distinct demographic and histological features.
  • Prognosis is influenced by tumor necrosis and cellular configuration, not traditional factors like histology or size.
  • Caudal rhabdomyosarcoma in neonates has a favorable outlook, suggesting potential for targeted therapeutic strategies.