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Comparison of three different treatment methods for generalized denture stomatitis
Y Kulak1, A Arikan, N Delibalta
1University of Marmara, Faculty of Dentistry, Nişantaşi, Istanbul.
The Journal of Prosthetic Dentistry
|September 1, 1994
Summary
For denture stomatitis, combining fluconazole with chlorhexidine offers superior results compared to fluconazole alone or new dentures. This combination effectively reduces inflammation and fungal presence.
Area of Science:
- Oral medicine
- Mycology
- Prosthodontics
Background:
- Denture stomatitis is a common oral condition.
- Fungal infections, particularly Candida, often contribute to its severity.
- Current treatments vary in efficacy.
Purpose of the Study:
- To compare the effectiveness of fluconazole, fluconazole plus chlorhexidine, and new dentures in treating generalized simple denture stomatitis.
- To evaluate the impact on palatal inflammation and candidal colonization.
Main Methods:
- 45 patients with denture stomatitis were divided into three groups.
- Group 1 received fluconazole (50 mg daily for 2 weeks).
- Group 2 received fluconazole plus chlorhexidine application to dentures (2 weeks).
- Group 3 received new dentures without medication.
Main Results:
- The fluconazole plus chlorhexidine group showed greater improvement in palatal inflammation.
- This combination also led to a significant decrease in candidal colonization.
- Both fluconazole alone and new dentures showed less improvement compared to the combination therapy.
Conclusions:
- Fluconazole combined with chlorhexidine is a highly effective treatment for generalized simple denture stomatitis.
- This combination therapy surpasses fluconazole alone or replacing dentures without medication.
- The findings support an integrated approach for managing denture-related oral conditions.