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Effects of sedatives and their solvents on the neutrophil granulocyte function
Y K Tian1, M Weiss, M Schneider
1Department of Anesthesiology, Tongji Hospital, Tongji Medical University, Wuhan.
Journal of Tongji Medical University = Tong Ji Yi Ke Da Xue Xue Bao
|January 1, 1994
Abstract:
We have examined the effects of commercially available preparations and drug-free solvents of Midazolam (Dormicum) and Propofol (Disoprivan) by N-formyl-methionyl-leucyl-phenylalanine (FMLP) -induced polymorphonuclear cell (PMN) chemiluminescence system. In the case of propofol and drug-free solvent, PMN chemiluminescence was suppressed. With Midazolam, only the active drug depressed PMN chemiluminescence.