Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Stage IV renal cell carcinoma

W Frank1, D Stuhldreher, R Saffrin

  • 1Department of Urology, University of Illinois, Chicago.

The Journal of Urology
|December 1, 1994
PubMed
Summary

For stage IV renal cell carcinoma patients, survival is not linked to gender, race, or age. However, larger tumors and multiple metastatic sites, especially bone and lung metastases, are associated with worse survival outcomes.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Olfactory dysfunction in SARS-CoV-2 infection: Focus on odorant specificity and chronic persistence.

American journal of otolaryngology·2021
Same author

Abscisic acid, cold and salt stimulate conserved metabolic regulation in the moss Physcomitrella patens.

Plant biology (Stuttgart, Germany)·2018
Same author

Comparison of a prepCheck-supported self-assessment concept with conventional faculty supervision in a pre-clinical simulation environment.

European journal of dental education : official journal of the Association for Dental Education in Europe·2018
Same author

The safety and efficacy of pediatric lingual tonsillectomy.

International journal of pediatric otorhinolaryngology·2016
Same author

Utility of a Paediatric Bleeding Questionnaire as a screening tool for von Willebrand disease in apparently healthy children.

Haemophilia : the official journal of the World Federation of Hemophilia·2015
Same author

Microwave-assisted synthesis of water-soluble, fluorescent gold nanoclusters capped with small organic molecules and a revealing fluorescence and X-ray absorption study.

Nanoscale·2015

Area of Science:

  • Oncology
  • Medical Statistics

Background:

  • Stage IV renal cell carcinoma (RCC) presents complex prognostic factors.
  • Understanding survival determinants is crucial for patient management and treatment strategies.

Purpose of the Study:

  • To investigate the relationship between various clinical factors and survival in patients with advanced RCC.
  • To identify key prognostic indicators for stage IV renal cell carcinoma.

Main Methods:

  • Retrospective analysis of data from 104 patients diagnosed with stage IV RCC.
  • Evaluation of factors including gender, race, age, tumor size, metastatic site (lung vs. bone), number of metastatic sites, and nephrectomy status.

Main Results:

  • No statistically significant survival differences were observed based on gender, race, or patient age.
  • Survival demonstrated a trend of decreasing with increasing tumor size.
  • Patients with multiple metastatic sites exhibited poorer survival compared to those with a single metastatic site.
  • Survival was worse for patients with combined bone and lung metastases versus those with isolated lung or bone metastases.
  • Apparent survival benefit in nephrectomy patients was attributed to confounding prognostic factors.

Conclusions:

  • Tumor size and the extent and type of metastasis are significant prognostic factors in stage IV RCC.
  • Gender, race, and age were not found to be significant predictors of survival in this cohort.
  • The role of nephrectomy in survival requires further investigation, considering potential confounding variables.

Related Experiment Videos