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Related Experiment Videos

Racial variation in gender frequency of calcium urolithiasis

E K Michaels1, Y Nakagawa, N Miura

  • 1Department of Urology, University of Illinois College of Medicine at Chicago.

The Journal of Urology
|December 1, 1994
PubMed
Summary

Calcium oxalate stones affect men more often, but this study found higher rates in women among Black and Hispanic populations. Further research is needed to understand these calcium urolithiasis gender differences.

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Area of Science:

  • Urology
  • Nephrology
  • Epidemiology

Background:

  • Calcium oxalate stones are a common condition, typically affecting men more than women.
  • Previous epidemiological data on calcium oxalate stones are limited, often derived from predominantly white populations or including diverse stone types.

Purpose of the Study:

  • To investigate the demographic and gender-specific prevalence of calcium oxalate stones across different racial and ethnic groups.
  • To compare stone prevalence in Asian populations with existing data from other demographics.

Main Methods:

  • Retrospective review of 444 patients treated for symptomatic renal and ureteral calculi at an urban hospital (189 white, 123 black, 132 Hispanic).
  • Inclusion of 260 patients from a Japanese university hospital.
  • Exclusion of patients with infection, uric acid, or cystine stones.

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Main Results:

  • Men were more frequently affected in white (62%) and Asian (64%) populations.
  • A reversal of gender frequency was observed in Black (68% women) and Hispanic (60% women) populations.
  • These findings indicate a higher prevalence of calcium urolithiasis in women than previously reported in certain demographics.

Conclusions:

  • Calcium urolithiasis prevalence varies significantly by gender across different racial and ethnic groups.
  • The study highlights a greater frequency of calcium stones in women within Black and Hispanic populations.
  • Further investigation into the etiologies behind these observed gender and racial disparities in calcium urolithiasis is warranted.