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Bladder outlet obstruction after multiple periurethral polytetrafluoroethylene injections
C D McKinney1, M J Gaffey, J Y Gillenwater
1Department of Anatomic Pathology, University of Virginia Health Sciences Center, Charlottesville.
The Journal of Urology
|January 1, 1995
Summary
Periurethral polytetrafluoroethylene (Teflon) injections for incontinence can cause delayed bladder outlet obstruction. A "teflonoma," a foreign body giant cell response, was identified as the cause 9 years post-injection.
Area of Science:
- Urology
- Pathology
Background:
- Periurethral polytetrafluoroethylene (Teflon) injections are used to treat urinary incontinence post-prostatectomy.
- Concerns exist regarding Teflon's potential for distant migration and granulomatous reactions.
Observation:
- A patient received Teflon injections for stress incontinence 9 years prior.
- The patient later developed bladder outlet obstruction.
Findings:
- Repeat transurethral resection was performed due to the obstruction.
- Pathology revealed a "teflonoma" – a foreign body giant cell response to Teflon – causing the blockage.
Implications:
- This case highlights a rare but significant long-term complication of Teflon injections.
- It suggests the need for vigilance regarding delayed obstructive symptoms after periurethral Teflon use.