Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Recommendation for studies of optimizing therapy protocols]

U Creutzig1, K Winkler

  • 1Universitäts-Kinderklinik, Münster.

Klinische Padiatrie
|July 1, 1994
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Breast assessment using next generation handheld ultrasound device based on silicon chips: a pilot study in senology.

Archives of gynecology and obstetrics·2026
Same author

From data to insights: Upscaling riverine GHG fluxes in Germany with machine learning.

The Science of the total environment·2024
Same author

Controlled Ordering of Topological Charges in an Exciton-Polariton Chain.

Physical review letters·2018
Same author

Exciton-polariton topological insulator.

Nature·2018
Same author

Treatment of very preterm preeclampsia via heparin-mediated extracorporeal LDL-precipitation (H.E.L.P.) apheresis: The Freiburg preeclampsia H.E.L.P.-Apheresis study.

Pregnancy hypertension·2018
Same author

Exciton-polariton trapping and potential landscape engineering.

Reports on progress in physics. Physical Society (Great Britain)·2016
Same journal

Guidance for the Diagnosis and Treatment of Rare Embryonal and Sarcomatous Brain Tumors-a Report from the Central Nervous System-International Registry for Rare Embryonal and Sarcomatous Tumors German Society of Pediatric Oncology and Hematology Study Group.

Klinische Padiatrie·2026
Same journal

Klinische Padiatrie·2026
Same journal

Association of Fat-free Mass Index and Body Mass Index on Pulmonary Function Tests in Children with Rheumatological Disease-associated Interstitial Lung Disease.

Klinische Padiatrie·2026
Same journal

Synchronous Differentiated Thyroid Carcinoma and Nonthyroid Malignancies in Pediatric Patients: A Registry-based Case Series.

Klinische Padiatrie·2026
Same journal

Intrauterine Ulceration of the Lower Limbs: A Not-so-rare Complication Following Vesicoamniotic Shunting with Somatex.

Klinische Padiatrie·2026
Same journal

Letter to the Editor Regarding the Article "Near-Fatal Asthma Due to Severe Airway Mucus Plugging in a 12-Year-Old Boy".

Klinische Padiatrie·2026
See all related articles

New European Community guidelines for Good Clinical Practice (GCP) in drug trials enhance patient protection and investigator responsibilities. These principles, including informed consent and ethics committee approval, are vital for pediatric oncology research.

Area of Science:

  • Clinical research ethics
  • Drug development regulations
  • Pediatric oncology studies

Context:

  • European Community introduced comprehensive Good Clinical Practice (GCP) guidelines in 1991.
  • These GCP standards are more extensive than the German drug regulatory act (AMG).
  • GCP guidelines encompass patient protection, investigator responsibilities, biometrics, and quality assurance.

Purpose:

  • To outline the principles of Good Clinical Practice (GCP) for medicinal product trials.
  • To highlight the adherence to ethical standards in pediatric oncology research, even when not strictly defined by national regulations.
  • To emphasize the importance of patient rights, risk-benefit assessment, informed consent, and ethics committee approval.

Summary:

  • European Community's 1991 Good Clinical Practice (GCP) guidelines set broad standards for medicinal product trials.

Related Experiment Videos

  • While many pediatric oncology studies fall outside the German drug regulatory act (AMG), they follow core GCP principles.
  • Key ethical considerations include patient safety, informed consent from patients and parents, risk justification, and ethics committee review.

    • Impact:

    • Ensures a high standard of patient protection and ethical conduct in clinical trials across Europe.
    • Promotes rigorous scientific methodology and data integrity in medicinal product research.
    • Facilitates the ethical advancement of treatments, particularly in sensitive areas like pediatric oncology.