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Effect of various detergents on the interaction between BK virus and susceptible cells

P Goldoni1, L Cattani, L Sinibaldi

  • 1Istituto Pasteur, Fondazione Cenci Bolognetti, Università di Roma La Sapienza, Italy.

The New Microbiologica
|July 1, 1994
PubMed

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Detergents are used to purify the integral proteins of the membrane. The hydrophobic portion of the detergent can replace membrane phospholipids while solubilizing the membrane proteins. When detergent monomers reach a specific concentration in a solution called critical micelle concentration (CMC), they form micelles. Above CMC, the concentration of the detergent monomers remains in equilibrium with the micelle. The number of detergent monomers present in the CMC varies for each detergent, and...