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[Tegalid distribution in the body of rats]
Meditsinskaia Parazitologiia I Parazitarnye Bolezni
|July 1, 1993
Abstract:
Pharmacokinetic studies of a new anthelminthic tegalid, made in this country, were carried out. The drug concentrations in biologic material were measured by high-pressure liquid chromatography. The drug was found to circulate for a rather long time in the blood, virtually not accumulating in any of the examined organs, except the liver. Tegalid pharmacokinetics can be fairly well approximated by a unicompartmental model with due consideration for its absorption.