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[Renal hypertension]

P Weidmann, F Reubi

    Schweizerische Medizinische Wochenschrift
    |December 11, 1976
    PubMed
    Summary
    This summary is machine-generated.

    Renal diseases cause about 15% of hypertension cases, influenced by sodium balance and the renin system. Diagnosis of renal artery stenosis is key, with similar drug treatments but distinct surgical options for renal hypertension.

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    Area of Science:

    • Nephrology
    • Cardiovascular Medicine
    • Hypertension Research

    Background:

    • Renal diseases account for approximately 15% of hypertension cases.
    • Key pathogenic factors include sodium-volume status and the renin-angiotensin system.
    • Hypertension duration and increased peripheral resistance are significant determinants of blood pressure levels.

    Purpose of the Study:

    • To review the causes, diagnosis, and treatment of renal hypertension.
    • To highlight the role of renal diseases in secondary hypertension.
    • To discuss diagnostic and therapeutic strategies for managing hypertension of renal origin.

    Main Methods:

    • Review of literature on renal hypertension.
    • Analysis of pathogenic mechanisms involving renal diseases.

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  • Discussion of diagnostic tools, including simultaneous renin activity measurement.
  • Overview of medical and surgical treatment options.

    • Main Results:

    • Renal parenchymal diseases and renal artery stenosis are common causes of secondary hypertension.
    • Renin-producing tumors are a less common but significant cause.
    • Simultaneous bilateral renal vein renin activity measurement is crucial for diagnosing renovascular hypertension.
    • Peripheral resistance increase is more critical than cardiac index in elevated blood pressure.

    Conclusions:

    • Effective management of renal hypertension requires understanding its specific pathophysiology.
    • Diagnostic accuracy, particularly for renal artery stenosis, is vital for guiding treatment.
    • Treatment strategies encompass both medical management, similar to essential hypertension, and surgical interventions tailored to the underlying renal condition.