Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Spasticity: a review

R R Young1

  • 1Department of Neurology, University of California, Irvine 92717-4275.

Neurology
|November 1, 1994
PubMed
Summary
This summary is machine-generated.

This study reviews spasticity treatments, focusing on tizanidine for multiple sclerosis (MS) and spinal cord injury patients. It evaluates when to treat spasticity and discusses new therapies for improved patient function and comfort.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Evaluation of the in vitro genetic toxicity of 4-(2, 4-dichlorophenoxy)butyric acid.

Mutation research·2000
Same author

Randomized, multicenter comparison of oral granisetron and oral ondansetron for emetogenic chemotherapy.

Pharmacotherapy·2000
Same author

Antispasticity medications.

Physical medicine and rehabilitation clinics of North America·1999
Same author

Diagnosis and medical management of multiple sclerosis.

The journal of spinal cord medicine·1998
Same author

Lack of genotoxic effects of sucrose acetate isobutyrate (SAIB).

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association·1998
Same author

Conservative management of spontaneous rupture of Kock orthotopic ileal reservoir.

Urology·1997
Same journal

Teaching Video NeuroImage: Tardive Blepharoclonus.

Neurology·2026
Same journal

Teaching NeuroImage: Latent Axonal Degeneration in Patient With Anterior Circulation Stroke.

Neurology·2026
Same journal

Incidental DWI-Positive Lesions in 2 Cohorts of CAA and CADASIL: Prevalence, Distribution, and Associations With Clinical Variables.

Neurology·2026
Same journal

Alpha-Synuclein Seed Amplification Assay in CSF, Skin, and Submandibular Gland From Incidental Lewy Body Disease and Parkinson Disease.

Neurology·2026
Same journal

Digital Semiology.

Neurology·2026
Same journal

Early Cerebral Edema Subtypes and Functional Outcome in Patients With Cerebral Venous Thrombosis: Insights From the CLOT-VENUS Registry.

Neurology·2026
See all related articles

Area of Science:

  • Neurology
  • Pharmacology

Background:

  • Spasticity is a common neurological symptom impacting patients with conditions like multiple sclerosis (MS) and spinal cord injury.
  • Understanding the pathophysiology of spasticity is crucial for effective patient management.

Purpose of the Study:

  • To review the definitions and pathophysiology of spasticity.
  • To evaluate the criteria for initiating spasticity treatment.
  • To discuss the efficacy of tizanidine and other novel therapies for spasticity.

Main Methods:

  • Literature review of spasticity definitions, pathophysiology, and treatment options.
  • Analysis of studies investigating tizanidine in MS and spinal cord injury.
  • Comparative discussion of pharmacologic and invasive therapeutic approaches.

Related Experiment Videos

Main Results:

  • Tizanidine has shown promise in managing spasticity in patients with MS and spinal cord injury.
  • Newer pharmacologic and invasive therapies offer potential benefits for reducing patient discomfort.
  • Treatment decisions for spasticity require careful evaluation of individual patient needs and potential functional gains.

Conclusions:

  • Effective management of spasticity can improve patient quality of life and potentially restore function.
  • Tizanidine represents a viable treatment option for spasticity in specific patient populations.
  • Ongoing research into novel therapies is essential for advancing spasticity treatment.