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Pharmacokinetics and pharmacodynamics of tizanidine
R C Roberts1, N J Part, R Pokorny
1Department of Medicine, Dundee University, Scotland, United Kingdom.
Neurology
|November 1, 1994
Abstract:
The relationship among tizanidine dose, plasma concentration, and antispastic action is linear in nature. Response to a given dose of this agent varies among patients, and determining the appropriate clinical dose requires individual titration.