Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Neuromyelitis optica

Y Igarashi1, H Oyachi, Y Nakamura

  • 1Department of Ophthalmology, Sapporo Medical College, Japan.

Ophthalmologica. Journal International D'Ophtalmologie. International Journal of Ophthalmology. Zeitschrift Fur Augenheilkunde
|January 1, 1994
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Transcranial magnetic stimulation of the posterior parietal cortex degrades accuracy of memory-guided saccades in humans.

Investigative ophthalmology & visual science·1995
Same author

Injury to cultured human vascular endothelial cells by copper (CuSO4).

Nihon eiseigaku zasshi. Japanese journal of hygiene·1992
Same author

Object losses and resolutions of women in middle adulthood.

The Tokai journal of experimental and clinical medicine·1992
Same author

Resolution of developmental tasks pertaining to prolongation of adolescence.

The Tokai journal of experimental and clinical medicine·1992
Same author

Importance of HLA-DRB1 genotyping in cadaveric renal transplantation.

Transplantation proceedings·1992
Same author

Therapy of a case of psychotic personality organization manifesting gender identity disorder.

The Tokai journal of experimental and clinical medicine·1992

Neuromyelitis optica (NMO) can manifest as sudden vision loss years before spinal cord inflammation. This case suggests NMO may be a form of multiple sclerosis.

Area of Science:

  • Neuroimmunology
  • Neurology
  • Ophthalmology

Background:

  • Neuromyelitis optica (NMO) is an autoimmune disorder targeting the central nervous system.
  • Typical NMO presentations involve optic neuritis and myelitis, often occurring concurrently or in close succession.

Observation:

  • An 11-year-old female presented with unilateral sudden visual loss.
  • Magnetic resonance imaging revealed multifocal lesions within the central nervous system.
  • Subacute myelitis was diagnosed 9 months after the initial visual deficit.

Findings:

  • The patient's clinical presentation, particularly the optic nerve and spinal cord involvement, strongly indicated neuromyelitis optica (NMO).
  • The significant delay between optic neuritis and myelitis is an atypical feature for NMO.

Related Experiment Videos

Implications:

  • This case supports the hypothesis that neuromyelitis optica (NMO) may represent a distinct variant of multiple sclerosis.
  • Understanding atypical presentations of NMO is crucial for accurate diagnosis and management.
  • Further research is warranted to elucidate the relationship between NMO and multiple sclerosis.