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Non-invasive Optical Imaging of the Lymphatic Vasculature of a Mouse
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Value of lymphangiography in the staging of Hodgkin lymphoma
E Libson1, A Polliack, R A Bloom
1Department of Radiology, Haddassah University Hospital, Jerusalem, Israel.
Purpose:
To evaluate the usefulness of lymphangiography in the staging of Hodgkin disease.
Materials And Methods:
The authors retrospectively evaluated the lymphangiograms of 39 previously untreated patients with Hodgkin disease (clinical stage, 1-2A). The patients had no evidence of bulky mediastinal nodal disease, and results of abdominal and pelvic computed tomographic examination were negative for parenchymal organ disease and retroperitoneal and mesenteric node involvement. The studies were officially interpreted as normal or abnormal. No attempt was made to differentiate benign reactive changes from tumor infiltration. All patients underwent confirmatory staging laparotomy.
Results:
Of the 39 patients, 29 had normal lymphangiograms. All 29 had normal lymph nodes at laparotomy. Of the 10 patients with abnormal lymphangiograms, only two had malignant infiltration of lymph nodes at laparotomy. The other eight showed benign reactive hyperplasia.
Conclusion:
Lymphangiography has no place in the management of Hodgkin lymphoma.
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