The evolution of the concentric lesions of atypical multiple sclerosis on MRI

We studied a patient with atypical multiple sclerosis (MS) using high field magnetic resonance image scanning and documented the evolution of the lesions from the acute phase to clinical remission. The acute lesions showed the clear concentric structure that is characteristic of Balo's concentric sclerosis on magnetic resonance imaging (MRI). Lesions were enhanced with gadolinium-DTPA (Gd-DTPA). Over a four-month period, the patient recovered clinically, with some evidence of residual intellectual impairment, and the MRI lesions regressed markedly, leaving hypointense areas on T1-weighted images in the corona radiata.