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The Sverdlovsk anthrax outbreak of 1979

M Meselson1, J Guillemin, M Hugh-Jones

  • 1Department of Molecular and Cellular Biology, Harvard University, Cambridge, MA 02138.

Science (New York, N.Y.)
|November 18, 1994
PubMed
Summary

An unusual anthrax outbreak in Sverdlovsk was likely caused by an aerosol release from a military facility, not contaminated meat. The spread pattern aligns with prevailing winds, supporting the airborne pathogen theory.

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Area of Science:

  • Epidemiology
  • Microbiology
  • Public Health

Background:

  • An anthrax epidemic occurred in Sverdlovsk in April-May 1979.
  • Official Soviet reports cited contaminated meat as the cause.
  • US agencies suggested an accidental release of anthrax spores from a military facility.

Observation:

  • Epidemiological data revealed a distinct zone of human and livestock cases.
  • This zone extended from the military facility southward, aligning with prevailing northerly winds.
  • Livestock deaths occurred farther south along the extended axis of this zone.

Findings:

  • The spatial distribution of cases strongly suggests an airborne source.
  • The prevailing wind direction correlated with the geographical spread of the outbreak.

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  • The evidence supports the hypothesis of an accidental aerosol release of Bacillus anthracis from the military facility.
  • Implications:

    • Understanding outbreak origins is crucial for public health preparedness.
    • This case highlights the potential risks associated with biological research facilities.
    • Investigating environmental factors like wind patterns aids in tracing disease transmission.