Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Ophthalmoplegia associated with AIDS

T R Hedges1

  • 1Department of Ophthalmology, Tufts University, New England Eye Center, Boston, Massachusetts.

Survey of Ophthalmology
|July 1, 1994
PubMed
Summary

This case study highlights a severe presentation of Acquired Immunodeficiency Syndrome (AIDS) with multiple organ involvement. It emphasizes the critical role of neuro-ophthalmology in diagnosing central nervous system complications in immunocompromised patients.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Prospective analysis of macular and optic disc changes after non-arteritic anterior ischemic optic neuropathy.

Journal francais d'ophtalmologie·2019
Same author

Sternutatory reflex induced by periocular needle insertion in patients receiving chronic botulinum toxin injections.

Parkinsonism & related disorders·2013
Same author

Optical coherence tomography of the retinal nerve fibre layer in mild papilloedema and pseudopapilloedema.

The British journal of ophthalmology·2005
Same author

Ophthalmic artery blood flow in humans.

The British journal of ophthalmology·2002
Same author

Flow velocity and pulsatility of the ocular circulation in chronic intracranial hypertension.

Acta neurologica Scandinavica·2002
Same author

Optical coherence tomography demonstrates subretinal macular edema from papilledema.

Archives of ophthalmology (Chicago, Ill. : 1960)·2001

Area of Science:

  • Neurology
  • Infectious Diseases
  • Ophthalmology

Background:

  • Acquired Immunodeficiency Syndrome (AIDS) can lead to opportunistic infections affecting multiple organ systems.
  • Central nervous system (CNS) involvement is a significant cause of morbidity and mortality in patients with advanced HIV/AIDS.

Observation:

  • A 34-year-old male with AIDS presented with cough, chest pain, fever, and a cavitating lung lesion.
  • He subsequently developed headache, a contrast-enhancing brain lesion, atrioventricular block, and hypernatremia.
  • Neuro-ophthalmological findings included facial droop, reduced vision, presumed cytomegalic inclusion retinitis, and mesencephalic syndrome.

Findings:

  • The patient's clinical course was rapidly progressive, suggesting disseminated disease.
  • Radiographic and neuro-ophthalmological findings pointed towards opportunistic infections or neoplasms affecting the CNS and eyes.
  • Differential diagnosis included toxoplasmosis, primary CNS lymphoma, cryptococcosis, and viral encephalitis.

Implications:

  • Prompt neuro-ophthalmological evaluation is crucial for early diagnosis and management of CNS complications in AIDS patients.
  • Aggressive diagnostic workup and treatment are necessary to improve outcomes in severely immunocompromised individuals.
  • This case underscores the importance of considering a broad differential diagnosis for neurological symptoms in the context of AIDS.

Related Experiment Videos