Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Immune-mediated muscle disease

R M Lewis1

  • 1Department of Veterinary Pathology, College of Veterinary Medicine, Cornell University, Ithaca, New York.

The Veterinary Clinics of North America. Small Animal Practice
|July 1, 1994
PubMed
Summary

This review discusses the immunopathogenic mechanisms behind myasthenia gravis, polymyositis, masticatory myopathy, and dermatomyositis. It aims to advance understanding and guide future research into these autoimmune muscle diseases.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Population dynamics of a long-term selection experiment in White Plymouth Rock chickens selected for low or high body weight.

Poultry science·2023
Same author

Non-invasive metabolomics biomarkers of production efficiency and beef carcass quality traits.

Scientific reports·2022
Same author

A massively multi-scale approach to characterizing tissue architecture by synchrotron micro-CT applied to the human placenta.

Journal of the Royal Society, Interface·2021
Same author

Genetic structure and admixture in sheep from terminal breeds in the United States.

Animal genetics·2020
Same author

Genome-wide association study to identify genetic loci associated with gastrointestinal nematode resistance in Katahdin sheep.

Animal genetics·2020
Same author

Human placental villi contain stromal macrovesicles associated with networks of stellate cells.

Journal of anatomy·2019

Area of Science:

  • Neurology
  • Immunology
  • Rheumatology

Background:

  • Myasthenia gravis, polymyositis, masticatory myopathy, and dermatomyositis are distinct neuromuscular and autoimmune disorders.
  • Understanding their shared and unique immunopathogenic mechanisms is crucial for effective treatment.

Purpose of the Study:

  • To review and synthesize current knowledge on the immunopathogenesis of these four conditions.
  • To highlight areas requiring further investigation for improved clinical outcomes.

Main Methods:

  • Literature review and synthesis of existing research on the immunopathogenic mechanisms.
  • Discussion of current understanding in relation to clinical manifestations.

Main Results:

  • The abstract does not contain specific results but discusses the mechanisms.
  • Key immunologic pathways implicated in muscle inflammation and neuromuscular junction dysfunction are considered.

Conclusions:

  • A comprehensive understanding of immunopathogenesis is essential for advancing research.
  • This review serves as a foundation for future studies aimed at elucidating complex disease mechanisms.

Related Experiment Videos