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A sodium magnetic resonance imaging study of acute cerebral ischaemia in the gerbil
K L Allen1, A L Busza, S C Williams
1Department of Neurochemistry, Institute of Neurology, London, U.K.
Abstract:
23Na magnetic resonance imaging has been used to investigate sodium changes during and after cerebral ischaemia in a gerbil model. The sodium signal decreased within 4 minutes of the onset of ischaemia, and subsequently increased between 4 and 8 minutes after the onset of reperfusion. These observations may be reflecting the redistribution of tissue sodium resulting from energy failure and recovery.