Septicemia occurring after colonoscopic polypectomy in a splenectomized patient taking corticosteroids

Area of Science:

• Infectious Diseases
• Gastroenterology
• Microbiology

Background:

• Transient bacteremia is a known, though rare, complication of colonoscopic procedures.
• Clinically significant bacteremia or endocarditis following colonoscopy is exceedingly uncommon.

Observation:

• This report details the first known case of septicemia involving Flavobacterium meningosepticum and Escherichia coli post-colonoscopic polypectomy.
• The patient presented with multiple risk factors for infection, including asplenia, diabetes, and long-term steroid use for autoimmune disorders, suggesting an immunocompromised state.

Findings:

• The patient developed severe sepsis attributed to a dual infection with F. meningosepticum and E. coli following the colonoscopic procedure.
• The immunocompromised status of the patient was identified as a likely predisposing factor for the development of bacteremia and subsequent septicemia.

Implications:

• This case underscores the potential risk of serious infections after endoscopic procedures, particularly in immunocompromised patients.
• Healthcare providers should maintain a high index of suspicion for unusual pathogens in immunocompromised individuals experiencing symptoms post-colonoscopy.
• Further research may be warranted to elucidate the specific mechanisms and risk factors for septicemia in this patient population.