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Advanced-stage ovarian carcinoma presenting during infertility evaluation
B Y Karlan1, R Marrs, L D Lagasse
1Department of Obstetrics and Gynecology, Cedars-Sinai Medical Center, Los Angeles, CA 90048.
American Journal of Obstetrics and Gynecology
|November 1, 1994
Summary
Advances in assisted reproductive techniques allow women to achieve pregnancy later in life. However, older women undergoing infertility treatments face an increased risk of ovarian cancer.
Area of Science:
- Reproductive Endocrinology
- Gynecologic Oncology
Background:
- Assisted reproductive techniques (ART) have extended female fecundity beyond natural reproductive ages.
- Ovarian cancer incidence rises with age, posing a significant health concern for aging populations.
Observation:
- An elevated risk of ovarian cancer is linked to factors such as incessant ovulation and infertility.
- Older patients seeking infertility treatment represent a demographic with potentially heightened ovarian cancer risk.
Findings:
- The study highlights the critical need to consider ovarian cancer in older infertility patients.
- Delayed diagnosis of ovarian cancer in this cohort can have serious consequences.
Implications:
- Clinicians must maintain a high index of suspicion for ovarian cancer in older women with infertility.
- Integrating ovarian cancer screening into the evaluation of older infertility patients is crucial for timely diagnosis and management.