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Immunoglobulin deficiency and recurrent postmenopausal endometritis
J W Barrington1, A Papagiannis, A Roberts
1Department of Obstetrics and Gynaecology, Llandough Hospital, Penarth, South Glamorgan, United Kingdom.
American Journal of Obstetrics and Gynecology
|November 1, 1994
Summary
Secretory immunoglobulin A (IgA) may decrease in postmenopausal women due to estrogen loss, potentially causing infections and bleeding. Regular immunoglobulin therapy is recommended for affected patients.
Area of Science:
- Immunology
- Gynecology
- Endocrinology
Background:
- Secretory immunoglobulin A (IgA) is crucial for mucosal immunity.
- Estrogen deficiency in postmenopausal women can lead to reduced secretory IgA levels.
- This reduction is linked to increased susceptibility to infections and unexplained bleeding.