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Angiosarcoma of the head and neck

W M Lydiatt1, A R Shaha, J P Shah

  • 1Department of Surgery, Head and Neck Service, Memorial Sloan-Kettering Cancer Center, New York, New York 10021.

American Journal of Surgery
|November 1, 1994
PubMed
Summary

Surgery is recommended for resectable head and neck angiosarcoma (AS), with radiation for aggressive features. Tumor size significantly impacts survival, with smaller lesions (<10 cm) showing better outcomes after wide local excision.

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Area of Science:

  • Oncology
  • Surgical Oncology
  • Head and Neck Surgery

Background:

  • Angiosarcoma (AS) is a rare and aggressive malignancy.
  • It presents a significant challenge due to its poor prognosis.

Purpose of the Study:

  • To evaluate the effectiveness of different treatment modalities for head and neck angiosarcoma.
  • To identify prognostic factors influencing survival in AS patients.

Main Methods:

  • Retrospective review of 18 patients with head and neck angiosarcoma treated between 1978 and 1992.
  • Analysis of treatment outcomes including surgery, radiation, and chemotherapy (doxorubicin hydrochloride).

Main Results:

  • The majority of tumors (16/18) occurred on the scalp and face.

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  • Overall 5-year survival was 33%, with 67% of patients dying of disease.
  • Tumor size was a critical prognostic factor: lesions >10 cm were universally fatal, while wide local excision of smaller lesions (<10 cm) resulted in 5-year survival in 4/6 patients.

    • Conclusions:

    • Surgery is the recommended primary treatment for resectable angiosarcoma.
    • Postoperative radiation is advised for tumors with unfavorable characteristics (large size, deep extension, etc.).
    • Elective neck treatment is not indicated for head and neck angiosarcoma.