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Updated: Jul 21, 2026
Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas
Published on: January 17, 2018
Sphenoid sinus involvement in neuroblastoma
M Kohli-Kumar1, J Barbosa, R E Harris
1Hematology/Oncology Division, Children's Hospital Medical Center, Cincinnati, OH 45229.
Purpose:
Malignancy of the sphenoid sinus, especially metastatic involvement, is an extremely rare event at any age and is usually associated with a poor prognosis. We present a case of a 5-year-old boy who underwent allogenic bone marrow transplantation for stage IV neuroblastoma.
Patients And Methods:
Three years later, he presented with an isolated lesion, histologically proven to be neuroblastoma, in the sphenoid sinus.
Results:
Partial excision of the tumor, followed by chemotherapy and radiotherapy, achieved a remission for 3 years.
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