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Related Experiment Videos

Bullous morphea: a distinct entity?

A Trattner1, M David, M Sandbank

  • 1Department of Dermatology, Beilinson Medical Center, Petah Tiqva, Israel.

The American Journal of Dermatopathology
|August 1, 1994
PubMed
Summary
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Radiation therapy for breast cancer can lead to morphea. In rare cases, this can evolve into bullous morphea, histologically resembling bullous lichen sclerosus et atrophicus.

Area of Science:

  • Dermatology
  • Oncology
  • Pathology

Background:

  • A 57-year-old woman with a history of breast cancer surgery and radiation therapy developed morphea.
  • Morphea is a localized sclerosing skin condition often associated with radiation therapy.

Observation:

  • Three years post-radiation, the patient developed a vesicular eruption within the morphea lesion.
  • This clinical presentation was diagnosed as bullous morphea.

Findings:

  • Histological examination of the vesicular component revealed features characteristic of lichen sclerosus et atrophicus.
  • This suggests a potential overlap or transformation between these dermatological conditions.

Implications:

  • Bullous morphea may represent a secondary manifestation of bullous lichen sclerosus et atrophicus developing on pre-existing morphea.

Related Experiment Videos

  • This case highlights a rare but important differential diagnosis in patients with post-radiation morphea and vesicular eruptions.