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[Plexiform fibrohistiocytic tumor]

U Sass1, J André, J C Noël

  • 1Service de Dermato-Vénéréologie des Hôpitaux Universitaires Saint-Pierre et Brugmann, Bruxelles, Belgique.

Annales De Dermatologie Et De Venereologie
|January 1, 1994
PubMed
Summary

Plexiform fibrohistiocytic tumour is a rare, low-grade malignancy. This study details two cases, highlighting histological features and diagnostic considerations for this uncommon neoplasm.

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Area of Science:

  • Oncology
  • Dermatopathology
  • Surgical Pathology

Background:

  • Plexiform fibrohistiocytic tumour (PFT) is a recently described rare neoplasm.
  • Characterized by low-grade malignancy, PFT necessitates wide surgical excision.

Observation:

  • Two cases of PFT are presented: a 58-year-old man with a hand mass and a 9-year-old boy with a chest nodule.
  • Histological examination revealed a dermal-hypodermal tumor with nodular proliferation of histiocytic-like cells, multinucleated osteoclastic-like cells, and fascicular fibroblastic-like cells in a plexiform pattern.

Findings:

  • Immunohistochemistry and ultrastructural analyses were performed.
  • Differential diagnoses and histogenesis of PFT were discussed.

Implications:

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  • This report contributes to the understanding of PFT's clinicopathological spectrum.
  • Further research may elucidate optimal management strategies for this rare tumor.